A crooked rancher forces Calamity to send a telegraph to the commander of a company of Texas Rangers authorizing an incursion into Mexico to round up a gang of rustlers.
After moving their cattle onto the Apache Indian reservation, Gorman accuses the Indians of cattle rustling. It's up to Buffalo Bill Jr. and his sis Calamity to prove the Indians' innocence.
Bill falls for a pretty girl when she and her father arrive in Wileyville. He and Judge Wiley convince the newcomers to buy the stagecoach line from its shifty owner.
Young Papito Gonzales is on the run from a man who claims that the mare and colt the boy has are his. Papito soon comes to Wileyville while on the run and gets into trouble with some men.