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An alcoholic journalist finds himself on the trail of a murderer after the police make him a suspect in their investigation.
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In 1828 Scotland, Edinburgh surgeon Dr. Knox does medical research on cadavers he buys from murderers Burke and Hare, without questioning the unethical procurement methods.
A group of friends travel to a remote Canadian island to hunt, only to be attacked by giant killer animals which have populated the place.
Jonathan Drake, while attending his brother's funeral, is shocked to find the head of the deceased is missing.