US government agents Ken Maynard and Hoot Gibson, aka "The Trail Blazers", make a deal with captured outlaw Duke Dillon to catch crooked Indian agent John Hampton, who has been using his authority to steal from the local tribe.
Hank Davis kills Jack Lewis to get his gold mine. Bruce Conway brings him in but then realizes Davis is the only one that knows where the mine is. Bruce and his pal Whitey rescue Davis from the lynch mob only to have Davis' gang catch them and leave them in the desert to die.
Mexican outlaw Zanti killed John Tobin's parents. John teams up with Dusty, also hurt by Zanti, to get the bad guy.
A prominent banker commits suicide. His son thinks otherwise and sets out to prove it.
