In 1828 Scotland, Edinburgh surgeon Dr. Knox does medical research on cadavers he buys from murderers Burke and Hare, without questioning the unethical procurement methods.
Dot Burton has acted as a decoy in a bank robbery and fails to get away. Her arrest attracts the attention of Ken Phillips (Frank Wilcox), a former childhood sweetheart who believe her innocent until she confesses.
Toni Le Brun, a beautiful Viennese singer, becomes the ward of the wardrobe mistress, of a Monte Carlo nightclub. Her benefactor, however, is actually a baroness, incognito.
Atlantic Flight was designed as a vehicle for Dick Merrill, a real-life pilot then very much in the news because of his record-breaking flights.