Twin brothers, half white and half Comanche, take different paths that overlap with Johnny Moon getting blamed for Notah's violent acts until the final confrontation in Rio Hondo.
The Apaches are on the warpath and the Army must defend them. Murphy's mission is to get a shipment of rifles, but it's stolen by greedy white traders with the help of mutinous soldiers.
As a child, Bill witnesses the murder of his family by four robbers. Fifteen years later, he embarks on his revenge. During his quest, he crosses paths with Ryan, an ex-con who wants the money the robbers owe him.
Escaped outlaw Jose Gomez returns to his home town pursued by bounty killer Luke Chilson. The towns people protect Gomez, unaware, at first, that he is now a changed and dangerous man.